Ángel
Rodríguez de Lera
Publicacions en què col·labora amb Ángel Rodríguez de Lera (10)
2012
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Modulation of RXR function through ligand design
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1821, Núm. 1, pp. 57-69
2011
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Retinoid X receptor gamma is implicated in docosahexaenoic acid modulation of despair behaviors and working memory in mice
Biological Psychiatry, Vol. 69, Núm. 8, pp. 788-794
2009
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Highly potent naphthofuran-based retinoic acid receptor agonists
ChemMedChem, Vol. 4, Núm. 5, pp. 780-791
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Modulating retinoid X receptor with a series of (E)-3-[4-hydroxy-3-(3- alkoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers
Journal of Medicinal Chemistry, Vol. 52, Núm. 10, pp. 3150-3158
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Selective, potent PPARγ agonists with cyclopentenone core structure
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 7, pp. 1883-1886
2008
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Nuclear receptor ligand-binding domains: Reduction of helix H12 dynamics to favour crystallization
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 64, Núm. 7, pp. 614-616
2007
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Deuterium exchange and mass spectrometry reveal the interaction differences of two synthetic modulators of RXRα LBD
Protein Science, Vol. 16, Núm. 11, pp. 2491-2501
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Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function
Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Núm. 44, pp. 17323-17328
2005
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Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies
Journal of Biological Chemistry, Vol. 280, Núm. 2, pp. 1625-1633
2004
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Rational design of RAR-selective ligands revealed by RARβ crystal stucture
EMBO Reports, Vol. 5, Núm. 9, pp. 877-882