Epilepsia extratemporal. Diagnóstico neuropatológico y evolución clínica postquirúrgica. Programa Nacional de Cirugía de Epilepsia, 2002-2017

  1. Bárbara O. Estupiñan Díaz 1
  2. Lilia M. Morales Chacón 1
  3. Lourdes Lorigados Pedre 1
  4. Margarita M. Báez Martín 1
  5. Nelson Quintanal Cordero 1
  6. Isabel Fernández Jiménez 1
  7. María Teresa Solomón Cardona 1
  8. Judith González González 1
  9. Juan E. Bender del Busto 1
  10. Manuel de Arriba Romanidy 2
  11. Héctor J. Gómez Suárez 2
  12. Mercedes R. Salinas Olivares 2
  13. Martha C. Ríos Castillo 3
  14. Aisel Santos Santos 2
  15. Zenaida M. Hernández Díaz 1
  16. María E. Morales Morales 2
  17. Daymarelys Charles Benoit 2
  1. 1 Centro Internacional de Restauración Neurológica (Ciren), La Habana
  2. 2 Instituto de Neurología y Neurocirugía, La Habana
  3. 3 Hospital Pediátrico Juan Manuel Márquez, La Habana
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Journal:
Panorama Cuba y Salud

ISSN: 1995-6797

Year of publication: 2019

Issue Title: XV Jornada de la Ciencia

Volume: 14

Issue: 1

Pages: 33-37

Type: Article

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Abstract

In centers dedicated to epilepsy surgery, about 20% of surgical interventions involve extratemporal epilepsy and the majority of cases correspond to the frontal lobe. The objective was to evaluate the neuropathological findings and the post-surgical clinical evolution in patients with drug-resistant extratemporal epilepsy treated in the National Epilepsy Surgery Program. From the database (Pathological Anatomy) of patients with drugresistant focal epilepsy, operated between 2002 and 2017, cases with extratemporal epilepsy were selected. All surgeries were guided by electrocorticography. Of the 64 patients studied, 17 were extratemporal. The average age at the time of surgery was 24.7 years In 66.66%, lesions were detected in imaging studies. Histological diagnoses were focal cortical dysplasia type I (4), IIa (1) and IIb (5); pilocytic astrocytoma (1); cavernous angioma (1); ganglioglioma (1); meningioangliomatosis (1); polymicrogyria (1) and descriptive (2). In the last evaluation, 8 patients continued with epileptic seizures (47.05%), 6 were without seizures (35.29%) and 3 did not attend the consultation. 26.56% of the patients corresponded with extra-temporal epilepsy, a result similar to that described in the literature. Neuropathological diagnoses are similar to those found in temporal lobe epilepsy with a predominant focal cortical dysplasia. Although the post-surgical outcome is inferior to temporary resections, surgery offers a benefit to these patients by reducing the frequency of seizures

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