Asociación entre valores de fuerza manual y capacidad cardiorrespiratoria en pacientes con diabetes mellitus tipo 2

  1. Rafa Baturone-Servan 1
  2. Manuel Costilla 1
  3. María Rebollo-Ramos 1
  4. Andrea González-Mariscal 1
  5. Laura Ávila-Cabeza-de-Vaca 1
  6. Alberto Marín-Galindo 1
  7. Adrián Montes-de-Oca-García 1
  8. Juan Corral-Pérez 1
  1. 1 ExPhy Research Group, Departamento de Educación Física e INiBICA, Universidad de Cádiz, España.
Proceedings:
Exercise, biomechanics and Nutrition

Publisher: Instituto Politécnico de Setúbal – Escola Superior de Educação

ISBN: 978-989-35059-3-9

Year of publication: 2023

Pages: 50

Type: Conference paper

GOOGLE SCHOLAR

Abstract

: Interleukin-6 (IL-6) and C-reactive protein (CRP) are blood markers used to determinethe inflammatory profile in patients with type 2 diabetes mellitus (T2DM). The aim of this studywas to examine the relationship between IL-6 and CRP levels with the level of physical fitnessand health in subjects with T2DM. A total of 95 subjects (53 males) diagnosed with T2DM wereincluded in the study. Plasma levels of IL-6 and CRP were obtained through a baseline bloodanalysis. Maximal oxygen consumption (VO2 max) was obtained through an incremental test ona cycle ergometer using indirect calorimetry. Handgrip strength was measured using adynamometer (Takei tkk5401). Body mass index (BMI) was calculated using the participants'weight and height. A linear regression model was used to determine the relationship betweeninflammatory markers and the other parameters analyzed in the study. Linear regression analysisshowed a significant association between IL-6 levels and BMI (β=0.279; p=0.007). Furthermore,CRP levels were significantly associated with BMI (β=0.332; p=<0.001), handgrip strength (β=-0.415; p=0.030), and VO2 max (β=0.282; p=0.041). The results of this study demonstrate thatpatients with T2DM with higher BMI levels displayed a higher inflammatory profile. However,higher levels of handgrip strength were associated with a better CRP profile. This highlights theimportance of using physical exercise as a tool to impact inflammatory parameters in individualswith T2DM.