Tumor de WilmsRevisión de nuestra experiencia en los últimos 15 años
- Laura Illade
- Carmen Hernandez-Marques
- Maria Cormenzana
- Álvaro Lassaletta
- Maitane Andión Catalán
- David Ruano
- Victoria Fioravantti
- Luis Madero López
ISSN: 1695-4033, 1696-4608
Year of publication: 2018
Volume: 88
Issue: 3
Pages: 140-149
Type: Article
More publications in: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría ( AEP )
Abstract
Introduction Wilms’ tumour is the most frequent renal tumour in children. Multi-modal treatment includes chemotherapy and surgery, with or without radiotherapy. The survival is excellent, with rates exceeding 90%. A review is presented on our experience over the last 15 years of treating Wilms’ tumour in Hospital Niño Jesús, Madrid. Patients and methods A retrospective study was conducted on 40 consecutive paediatric patients diagnosed with nephroblastoma between 2002 and 2016 in the Hospital Niño Jesús in Madrid. The clinical characteristics, diagnostic methods, treatment, and follow-up were analysed. Results Of the 40 patients, 23 were boys, with a median age at diagnosis of 2.5 years (range, 4 months-15 years). Three patients underwent initial nephrectomy, three received a fine needle aspiration biopsy, followed by chemotherapy, and 34 patients started pre-operative chemotherapy directly. The median follow-up of the patients was 6.75 years (range, 10 months - 13.92 years). Two patients died from disease progression. There were no treatment-related deaths. Overall survival and event-free survival at 5 years was 94.6±3.7% and 89.4±5%, respectively. Conclusion Wilms’ tumour treatment is a success of modern medicine, currently achieving a survival rate of 95% in our series.