Are body composition and physical fitness associated with total antioxidant capacity?

Resumen

Objectives: To determine the associations of body composition and physical fitness with total antioxidant capacity (TAC) in olderadults. Methods: A total of 46 older adults (20 females) of 68.52±3.08 years were included from the wave 1 of INTERMAE project (funded by Consejería de Salud y Familias and FEDER ,PI-0002-2017, clinical trial NCT03923712). Body composition was measured using a multifrequency bioimpedance. Physical fitness was divided into three domains: i) cardiorespiratory fitness, measured by peak oxygen consumption (VO2peak) by the modified Bruce incremental test and 6-minute walking test; ii) muscle strength, assessed by handgrip, 30 seconds-chair stand and arm curl tests; and iii) coordination-agility, assessed by 8- foot up and go test and 6-meter gait speed at normal and fast pace. Plasma TAC levels were measured by using a modified ferric reducing antioxidant power. Simple linear regression analyses were performed to calculate the associations of TAC with body composition and fitness tests. Results: No associations were found for body composition and TAC except for fat and fat free mass (both absolute and percentage) which showed a negative and positive association with TAC, respectively (p<0.04). VO2peak was associated withTAC (absolute, =0.29, p<0.05), however, no association was found β-adrenergic agonists helps in the speed of response. These for 6-minutes walking test. Regarding muscle strength, significant associations were found for handgrip ( =0.41) and chair stand β-adrenergic agonists helps in the speed of response. These tests ( =0.31) but not for arm curl test with TAC. Finally, β-adrenergic agonists helps in the speed of response. Thesecoordination-agility, 8-foot up and go test and 6-meter gait speed tests were associated ( =-0.51, 0.39, 0.45, respectively) with TAC. β-adrenergic agonists helps in the speed of response. These Conclusions: Body weight does not seem to be associated with TAC but a relevant role of fat mass and fat free mass on TAC was reported. Moreover, almost all physical fitness tests were associated with with TAC which could suggest a potentialmechanism by which fitness prevent frailty. However, further analysis including accelerometer-measured physical activity anddiet remained to be performed to complement these findings.