Estimación de fibrosis hepática y obesidad en población laboral española durante la pandemia COVID-19:variables relacionadas

Abstract

Introduction. Non-alcoholic fatty liver is the most common liver disease in the world, usually asymptomatic and related, among other factors, to obesity. Method. Cross-sectional descriptive study in 815 workers between 18-66 years old, during the health surveillance of the participating companies from March 2020-June 2021. The FIB-4 Index for liver fibrosis calculator is used and relationships with sociodemographic variables, adiposity indices, eating habits and physical activity are based on the use of PREDIMED and IPAQ questionnaires. Results. Grade 2 obesity correlates with intermediate risk of progression to hepatic fibrosis estimated with FIB-4. The variables that show a statistically significant relationship with a higher risk of liver fibrosis according to FIB-4 are age, level of education and level of visceral fat. Conclusions. Men have a higher prevalence of intermediate values of FIB-4, but it does not show a significant relationship with adherence to the Mediterranean diet or with the practice of physical activity in both genders. Age over 50 YEARS multiplies by 8.16 the possibility of having intermediate values in FIB-4 and a high waist-hip ratio is related to a 1.82-fold higher risk of developing liver fibrosis with FIB-4.