Cáncer y trabajo. Una visión holística preventiva de una enfermedad compleja

  1. Mª Teófila Vicente-Herrero 13
  2. Mª Victoria Ramírez Iñiguez de la Torre 12
  1. 1 Grupo cáncer y Trabajo-Asociación Española de Especialistas en Medicina del Trabajo-AEEMT (España).
  2. 2 Grupo Correos-SEPI-Albacete y Cuenca.
  3. 3 Grupo ADEMA-SALUD del Instituto Universitario de Ciencias de la Salud-IUNICS Illes Balears (España)
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Revista:
Academic Journal of Health Sciences: Medicina Balear

ISSN: 2255-0560

Año de publicación: 2023

Volumen: 38

Número: 1

Páginas: 9-17

Tipo: Artículo

DOI: 10.3306/AJHS.2023.38.01.9 DIALNET GOOGLE SCHOLAR lock_openIbdigital editor

Resumen

Introduction: Cancer and its prevention is currently a public health priority in all countries. In occupational cancer, the World Health Organisation estimates that each year at least 200,000 people worldwide die of cancer related to their workplace. Cancer is considered a multifactorial disease that may not be due to a single cause but to a sequence of exposures over a lifetime.Methodology: A search was conducted in July 2022 in PubMed/Medline databases, using as keywords and MeSH terms: health promotion and cancer, Workplace and cancer, Environment and cancer; exposome and Cancer.Forty-three original articles, systematic reviews and review articles related to cancer and occupational and environmental exposure were selected. Studies with non-relevant information were excluded, with the authors commenting on 11 of these articles with relevant information from an occupational point of view.Results: The etiology of cancer requires studies that include genetic alterations, occupational and environmental exposures as well as the assessment of socio-economic aspects in affected individuals to provide an evidence base for prevention. Some environmental exposures associated with occupational exposures increase the risk of cancer: indoor and outdoor air pollution, pesticides, some endocrine disruptors, carcinogenic metals and metalloids, and radiation among others.Conclusions: Lifestyle factors, increased screening and ageing cannot fully explain the current increasing global incidence of cancer. The joint assessment of environmental, occupational and occupational exposures facilitates the preventive view within the concept of occupational exposome, although it requires costly procedures not available to all.

Referencias bibliográficas

  • Pelosi E, Castelli G, Testa U. Understanding mechanisms of cancer initiation and development supports the need for an implementation of primary and secondary cancer prevention. Ann Ist Super Sanita. 2019;55(4):371-9.
  • World Health Organization. OMS/OIT: Casi 2 millones de personas mueren cada año por causas relacionadas con el trabajo. Disponible en: https://www.who.int/es/news/item/16-09-2021-who-ilo-almost-2-million-people-die-from-work-related-causes-each-year. (Consultado el 17 de julio de 2022).
  • World Health Organization. Prevención y control del cáncer en el contexto de un enfoque integrado. Disponible en: https://apps.who.int/iris/handle/10665/275677. Consultado el 17 de julio de 2022.
  • Marant Micallef C, Shield KD, Baldi I, Charbotel B, Fervers B, Gilg Soit Ilg A, Guénel P, et al. Exposiciones ocupacionales y cáncer: una revisión de agentes y estimaciones de riesgo relativo. Occupational and Environmental Medicine 2018;75:604-14.
  • Vineis P, Kriebel D. Causal models in epidemiology: past inheritance and genetic future. Environ Health. 2006;5:21.
  • Wild CP, Scalbert A, Herceg Z. Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk. Environ Mol Mutagen. 2013;54(7):480-99.
  • Scheen AJ. Environment and cancer: not easy to dissect the exposome. Rev Med Liege. 2021;76(5-6):337-43.
  • Belpomme D, Irigaray P, Hardell L, Clapp R, Montagnier L, Epstein S, Sasco AJ. The multitude and diversity of environmental carcinogens. Environ Res. 2007;105(3):414-29.
  • Irigaray P, Newby JA, Clapp R, Hardell L, Howard V, Montagnier L, Epstein S, Belpomme D. Lifestyle-related factors and environmental agents causing cancer: an overview. Biomed Pharmacother. 2007;61(10):640-58.
  • Boffetta P. Human cancer from environmental pollutants: the epidemiological evidence. Mutat Res. 2006;608(2):157-62.
  • Chen KC, Tsai SW, Shie RH, Zeng C, Yang HY. Indoor Air Pollution Increases the Risk of Lung Cancer. Int J Environ Res Public Health. 2022;19(3):1164.
  • Lagunas-Rangel FA, Liu W, Schiöth HB. Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients? Int J Environ Res Public Health. 2022;19(4):2064.
  • Ciocan C, Franco N, Pira E, Mansour I, Godono A, Boffetta P. Methodological issues in descriptive environmental epidemiology. The example of study Sentieri. Med Lav. 2021;112(1):15-33.
  • Pukkala E, Martinsen JI, Lynge E, Gunnarsdottir HK, Sparén P, Tryggvadottir L, Weiderpass E, Kjaerheim K. Occupation and cancer - follow-up of 15 million people in five Nordic countries. Acta Oncol. 2009;48(5)646790.
  • Ilbawi AM, Anderson BO. Cancer in global health: how do prevention and early detection strategies relate? Sci Transl Med. 2015;7(278):278cm1.
  • Roquelaure Y, Luce D, Descatha A, Bonvallot N, Porro B, Coutarel F. Un modèle organisationnel de l’exposome professionnel [Occupational exposome: An organisational model]. Med Sci (Paris). 2022;38(3):288-93.
Fuente de los datos: Dialnet